Outcome of children with isolated microscopic hematuria without renal biopsy

Introduction: Hematuria (presence of >5 RBCs/HPF) may be a transient outcome or indicator of significant renal disorder in children. Children with neither symptoms of a disease nor a physical abnormality who have microscopic hematuria should be placed in the category of isolated microscopic hematuria (IMH). Objectives: The aim of this study was to evaluate the course of IMH. Patients and Methods: This investigation is an observational study of 124 patients referred to pediatric nephrology clinic from 2002-2012 with IMH. Results: In this study, 124 patients, 40 (32.3%) female and 84 (67.8%) male were evaluated. The mean age was 5.6±2.4 years. The mean follow-up time was 14.3 ± 14.4 months. This mean for 45.2% of the patients, was less than 6 months and for 4% of the patients, it was more than 4 years. The reasons for discovering hematuria were; 66.1% after routine evaluation, 21.8% due to positive family history and 12.1% after urinary tract infection (UTI). In this study, all the laboratory tests and kidney function were normal, except for the presence of microscopic hematuria. Conclusion: It was concluded that IMH without renal failure, hypertension (HTN) and proteinuria is a benign condition with no need for kidney biopsy.