Title of article
Synthesis, characterization and antibacterial evaluation of chalcones containing thiazole moiety
Author/Authors
Deshmukh, Ramchandra N. Bharati Vidyapeeth’s College of Engineering, Kolhapur, Maharashtra, INDIA , Rashinkarb, Gajanan S. Department of Chemistry - Shivaji University, Kolhapur, Maharashtra, INDIA , Dengle, Ramesh V. Vivekanand College, Kolhapur, Maharshtra, INDIA
Pages
5
From page
1765
To page
1769
Abstract
Chalcones (5a-j) containing thiazole moiety were synthesized by Claisen-Schmidt condensation between 1-(4-methyl-2-(pyridine-3-yl)thiazol-5-yl)ethanone (3) and variously substituted aryl/heteryl aldehydes (4a-j) in good yield. All the synthesized compounds were characterized by FTIR, 1H NMR, 13C NMR, mass spectroscopy and elemental analysis data. The synthesized compounds were evaluated for their in vitro antibacterial activity against Gram-positive and Gram-negative bacteria and showed moderate to good antibacterial activity.
Keywords
Thiazole , Chalcone , Antibacterial , Synthesis , Aldehydes
Journal title
Astroparticle Physics
Serial Year
2016
Record number
2435869
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