Extension Without Malignant Changes in Oral Melanotic Macule: A Report of Two Cases and Review of the Literature

Introduction: Oral melanotic macule (OMM) is a benign discoloration of oral mucosa that is identified by an increase in melanin pigmentation. The diagnosis of OMMis critical because it may have a similarity to oral melanoma at early stages. Therefore, microscopic examination is necessary to confirm the accurate diagnosis of the OMM. Case Presentation:We report two cases of discoloration in the oral cavity with asymmetry and border irregularity. After obtaining informed consent,weperformed an excisional biopsy thatshowedthe increase of melanin adjacent to the basalandparabasal layers of squamous epithelial cells, confirming the diagnosis of OMM. Conclusions: Early melanoma can have a similar clinical appearance to OMM. Therefore, an excisional biopsy can be done and the diagnosis of OMMcan be confirmed by microscopic examination.