Title of article
AntiGlomerular Basement Membrane Disease With Thrombotic Thrombocytopenic Purpura
Author/Authors
Alirezaei ، Amirhesam - Shahid Behesht University of Medical Sciences, School of Medicine Shahid Beheshti University of Medical Sciences , Bakhtiyari ، Mahmood - Alborz University of Medical Sciences , Zare ، Elham - Shahid Behesht University of Medical Sciences
Pages
7
From page
106
To page
112
Abstract
We report a 25yearold man who was initially presented with Rapidly Progressive Glomerulonephritis (RPGN) in Shahid Modarress Hospital, Tehran, Iran. His diagnosis was AntiGlomerular Basement Membrane (AntiGBM) disease that was confirmed by kidney biopsy, as his serum AntiGBM antibody was undetectable. Although the patient was on cyclophosphamide and high dose prednisolone, he developed Thrombotic Thrombocytopenic Purpura (TTP). We initiated treatment with a high dose of prednisone and plasmapheresis. Because of his poor response, rituximab was administered. After that, the patient #x2019;s hematologic criteria and clinical symptoms improved to an acceptable level. Our case is a unique form of negative serum AntiGBM antibody disease which was complicated with TTP #xA0;and responded to treatment with rituximab
Keywords
Antglomerular basement , Glomerulonephrits , TTP
Journal title
Case Reports in Clinical Practice
Serial Year
2018
Journal title
Case Reports in Clinical Practice
Record number
2456391
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