• Title of article

    Gold Nanoparticles/Cysteic Acid Modified Electrode for Simultaneous Electrochemical Determination of Tramadol and Paracetamol

  • Author/Authors

    Hassanvand, Zahra Department of Chemistry - Razi University, Kermanshah, Iran , Jalali, Fahimeh Department of Chemistry - Razi University, Kermanshah, Iran

  • Pages
    12
  • From page
    393
  • To page
    404
  • Abstract
    Electrochemical deposition of gold nanoparticles (AuNPs) and l-cysteine on glassy carbon electrode was carried out to prepare a modified electrode. The fabricated sensor showed good sensitivity and selectivity for simultaneous determination of paracetamol and tramadol by square wave voltammetry. Linear ranges of 0.10-10.7 μM (paracetamol) and 0.50-63.6 μM (tramadol) were obtained with detection limits of 0.03 and 0.17 μM, respectively. The proposed electrode was used successfully in the simultaneous determination of the drugs in spiked human plasma samples.
  • Keywords
    Square wave voltammetry , Gold nanoparticles , Cysteic acid , Modified electrode , Paracetamol , Tramadol
  • Journal title
    Astroparticle Physics
  • Serial Year
    2019
  • Record number

    2460274