Title of article
A novel synthesis of diastereomerically pure spiro- oxindolopyrrolizidines and oxindolopyrrolidines via cycloaddition reactions of azomethine ylides
Author/Authors
Taghizadeh ، Mohammad Javad - Imam Hossein University , Jadidi ، Khosrow - Shahid Beheshti University
Pages
5
From page
57
To page
61
Abstract
An efficient one-pot three-component procedure for the synthesis of new chiral spiro oxindolopyrrolidines/pyrrolizidines with highly regio- and diastereo-enantio selective from 1,3-dipolar cycloaddition of azomethine ylides and chiral menthol-drived trans-cinnamic are described. The mechanism of the reaction is discussed on the basis of the assignment of the absolute configuration of one of the cycloaddition products, which was obtained by single crystal X-ray analysis.
Keywords
Chiral spiro oxindolopyrrolidines , pyrrolizidines , azomethine ylides , chiral menthol , drived trans , cinnamic , isatin , sarcosine
Journal title
Iranian Chemical Communication
Serial Year
2015
Journal title
Iranian Chemical Communication
Record number
2460965
Link To Document