Title of article
Antibacterial Activity of Some New Azole Compounds
Author/Authors
Sadeghpour, Hossein Department of Medicinal Chemistry - School of Pharmacy - Shiraz University of Medical Sciences, Shiraz , Ghasemi, Yones Pharmaceutical Sciences Resaerch Center and Department of Biotechnology - School of Pharmacy - Shiraz University of Medical Sciences, Shiraz , Rezaie, Zahra Department of Medicinal Chemistry - School of Pharmacy - Shiraz University of Medical Sciences, Shiraz , Khabnadideh, Soghra Department of Medicinal Chemistry - School of Pharmacy - Shiraz University of Medical Sciences, Shiraz , Falahzadeh, Zahra Pharmaceutical Sciences Resaerch Center - Shiraz University of Medical Sciences
Pages
4
From page
267
To page
270
Abstract
We have previously synthesized new N-alkylated azoles (1b-7b) as antifungal
agents. Here, we evaluated the antibacterial activities of these compounds against
two gram positive and two gram negative bacteria by broth microdilution method.
The aminothiazole derivative (7b) showed an excellent antibacterial activity. Other
compounds exhibited moderate to good antibacterial activity. All compounds are more
active against gram positive than against gram negative bacteria.
Keywords
Aminothiazole , Antibacterial , Benzimidazole , Benzotriazole
Journal title
Astroparticle Physics
Serial Year
2012
Record number
2481794
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