Title of article
Is Mitochondria Biogenesis and Neuronal Loss Prevention in Rat Hippocampus Promoted by Apigenin?
Author/Authors
Chirumbolo, Salvatore Department of Neuroscience - Biomedicine and Movement Sciences - Unit of Human Anatomy - University of Verona - Italy
Pages
4
From page
541
To page
544
Abstract
In this Correspondence, a comment to a recent paper by Nikbakht et al., published in the latest ssu of this Journal is reported. The flavone apigenin can exert both its anti-oxidant potetial via the usual enzymatic ROS scavenging system and the mitochondria biogenesis via the PGC-1α/ TFAM/NRF-1 pathway. The very interesting paper by Nikbakht et al, may earn more insighful clues about the activity of apigenin in the prevention of the rat hippocampus neuronal loss caused by the Aβ25-35 injection.
Keywords
Rat , Apigenin , Neuronal loss , Mitochondria , Biogenesis , PGC-1alpha
Journal title
Basic and Clinical Neuroscience
Serial Year
2019
Record number
2499947
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