• Title of article

    McCune-Albright Syndrome; Polyostotic Fibrous Dysplasia, Hyperthyroidism and Café-Au-Lait Spots: A Case Report

  • Author/Authors

    Naseri, Rozita Department of Internal Medicine - School of Medicine - Kermanshah University of Medical Sciences , Jamadi, Zahra School of Medicine - Shahid Beheshti University of Medical Sciences, Tehran , Saeedinia, Arezoo Department of Internal Medicine - Shahid Labbafinejad Hospital - Shahid Beheshti University of Medical Sciences, Tehran

  • Pages
    4
  • From page
    1
  • To page
    4
  • Abstract
    McCune-Albright syndrome (MAS) is a uncommon disease caused by a mutation in the GNAS1 gene and is associated with exposure to dysplasia of polypropylene fibers (PFD), Café-au-lait spots and hyperfunctioning endocrinopathies mostly including hyperthyroidism and precocious puberty (PP). The present article describes an eight-year-old boy presenting to a physician for the first time at the age of four owing to recurrent pathological fractures of the femur as well as hyperthyroidism, which was found in physical examinations to be associated with several nodules in the thyroid.
  • Keywords
    McCune-Albright Syndrome (MAS) , Polyostotic Fibrous Dysplasia (PFD) , Hyperthyroidism , GNAS1 Gene
  • Journal title
    Journal of Kermanshah University of Medical Sciences
  • Serial Year
    2019
  • Record number

    2501656