Green synthesis and study of antioxidant activity of benzofuran derivatives

An efficient procedure for the synthesis of benzofuran derivatives employing 1-(6-hydroxy-2-isopropenyl-1- benzofuran-yl)-1-ethanone that is extracted from Petasites hybridus and activated acetylenic compounds in the presence of KF/CP (NPs) as a heterogeneous base nanocatalyst in water at 80 oC is investigated. Also, the antioxidant activity of some synthesized compounds was studied. The workup of reaction is simple and the products can be separated easily from the reaction mixture. KF/CP NPs show a good improvement in the yield of the product. The catalyst displayed significant reusable activity..