The Effects of Eight Weeks of Aerobic Training and Resveratrol Supplementation on Oxidative Stress Markers in Women with Metabolic Syndrome

Background: The aim of the present study was to investigate the effects of eight weeks of aerobic training and resveratrol supplementation on oxidative stress markers in women with metabolic syndrome. Methods: In a double-blind study, 32 overweight women with metabolic syndrome were randomly categorized into four groups of aerobic exercise, resveratrol supplement, exercise plus the supplement, and control. The exercise protocol was eight weeks long with three 60-min sessions every week. The supplement and placebo dose was 400 mg/day. Serum malondialdehyde and total antioxidant capacity were measured at the beginning and end of the study. Results: Eight weeks of aerobic exercise led to a significant decrease in malondialdehyde and a significant increase in total antioxidant capacity in the exercise, exercise plus supplement, and resveratrol supplement groups compared with the control group, with the greatest effect being observed in the exercise plus supplement group. Conclusion: Using resveratrol along with aerobic exercises can be effective in attenuating oxidative stress. Further studies with larger sample size are needed to confirm these results.