Title of article
In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)
Author/Authors
IMRAN, Muhammad University of the Punjab, PAKISTAN , IQBAL, Javed Punjab University - Institute of Chemistry, PAKISTAN , IQBAL, Shahid University of Sargodha - Department of Chemistry, PAKISTAN , IJAZ, Nazia University of Sargodha - Department of Chemistry, PAKISTAN
From page
67
To page
72
Abstract
Some new transition metal complexes of ciprofloxacin-imines derived from ciprofloxacin and p-substituted anilines were synthesized and characterized on the basis of physical properties, conductance measurements, elemental analysis, UV/Vis., infraredand nuclear magnetic resonance spectroscopy. These ligands as well as their metal complexes were also evaluated for their antibacterial activity against several bacterial strains, such as Staphylococcus aureus, Bacillus subtilus, Salmonella typhae, and E. coli.It was found that metal complexes are more antibacterial as compared to uncomplexed ligands. The present study was carried outin search of a target antibiotic instead of a broad spectrum one.
Keywords
Ciprofloxacin imines , coordination compounds , antibacterial activity
Journal title
Turkish Journal of Biology
Journal title
Turkish Journal of Biology
Record number
2533694
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