Title of article
Anti-infl ammatory activity of Anthemis aciphylla var. aciphylla Boiss.
Author/Authors
BALTACI, Sinem Ege University - Faculty of Pharmacy - Department of Pharmacognosy, TURKEY , KOLATAN, Hatice Efsun Dokuz Eylül University - Department of Laboratory Animal Science, TURKEY , YILMAZ, Osman Dokuz Eylül University - Department of Laboratory Animal Science, TURKEY , KIVÇAK, Bijen Ege University - Faculty of Pharmacy - Department of Pharmacognosy, TURKEY
From page
757
To page
762
Abstract
Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-infl ammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet- induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.
Keywords
Anthemis aciphylla , anti , inflammatory activity , carrageenin , paw edema , cotton pellet
Journal title
Turkish Journal of Biology
Journal title
Turkish Journal of Biology
Record number
2533924
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