Title of article
Investigation of the genotoxic and antigenotoxic properties of essential oils obtained from two Origanum species by Drosophila wing SMART assay
Author/Authors
DEMİR, Eşref Akdeniz University - Faculty of Sciences - Department of Biology, Turkey , KAYA, Bülent Akdeniz University - Faculty of Sciences - Department of Biology, Turkey , MARCOS, Ricard Autonomous University of Barcelona - Department of Genetics and Microbiology, Mutagenesis Group, Spain , MARCOS, Ricard Biomedical Research Center Network for Epidemiology and Public Health, Spain , KOCAOĞLU CENKCİ, Serap Akdeniz University - Antalya School of Health - Department of Nutrition and Diet, Turkey , ÇETİN, Hüseyin Akdeniz University - Faculty of Sciences - Department of Biology, Turkey
From page
129
To page
138
Abstract
In this study, essential oils extracted from 2 species of oregano, Origanum onites L. and Origanum minutiflorum O.Schwarz P.H.Davis, were assayed for genotoxicity using the somatic mutation and recombination test (SMART) in Drosophila melanogaster. Results indicated that there is no significant genotoxic effect of the 2 oils tested. In addition, the antigenotoxic activities of these oils against potassium dichromate (K2Cr2O7) and cobalt chloride (CoCl2) were tested. Results indicated that essential oil cotreatments were able to abolish the genotoxic effects induced by the 2 metal compounds. It is suggested that the observed effects can be linked to the antioxidant properties of the selected essential oils. Moreover, these in vivo results will contribute to the antigenotoxicity database of the 2 Origanum species used in this study.
Keywords
Drosophila , antigenotoxicity , Origanum onites , Origanum minutiflorum , cobalt chloride , potassium dichromate
Journal title
Turkish Journal of Biology
Journal title
Turkish Journal of Biology
Record number
2534139
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