Title of article
Synthesis and in-vitro antimicrobial screening of 3-cinnamoyl coumarin and
Author/Authors
Gholap, Somnath S Department of Chemistry, PadmashriVikhePatil College, Pravaranagar (LoniKd), Tal- Rahata, Dist -Ahmednagar, Pin-413713,(MS), India., هندوستان , Deshmukh, Umesh P Department of Chemistry, PadmashriVikhePatil College, Pravaranagar (LoniKd), Tal- Rahata, Dist -Ahmednagar, Pin-413713,(MS), India., هندوستان , Tambe, Macchindra S Department of Chemistry, PadmashriVikhePatil College, Pravaranagar (LoniKd), Tal- Rahata, Dist -Ahmednagar, Pin-413713,(MS), India, هندوستان
From page
171
To page
176
Abstract
An efficient synthesis of some novel coumarin derivatives via 1, 4- Michael addition of indole to coumarinchalcones catalyzed by cellulose sulphonic acid (CSA) under solvent free conditions is described. The corresponding Michael addition products were obtained in good to excellent yield. The synthesized compounds were screened for their antibacterial activity against E. coli, S. aureusand anti-fungal activity against C. albicans. All the synthesized compounds show moderate to good antimicrobial activity.
Keywords
Cellulose sulphonicacid(CSA) , 3 , acetyl coumarinn , chalcones , indole , 1 , 4 , Michael addition , antibacterial activity ,
Journal title
Iranian Journal of Catalysis
Journal title
Iranian Journal of Catalysis
Record number
2550349
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