• Title of article

    Macrocytic anemia and thrombocytosis associated with thymoma: A case report

  • Author/Authors

    Grumbeck، Elke نويسنده , , Aiginger، Paul نويسنده , , Gisslinger، Bettina نويسنده , , Geissler، Klaus نويسنده , , Thalhammer-Scherrer، Renate نويسنده , , Gisslinger، Heinz نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    -37
  • From page
    38
  • To page
    0
  • Abstract
    We present an elderly patient with mantle cell leukemia who was successfully treated with lowdose cyclophosphamide (CY). A 76-year-old female was diagnosed as mantle cell leukemia based on abnormal lymphocytosis and splenomegaly without lymphadenopathy. She was orally treated with 50 mg of CY daily and had continuous remission over 4 years. Rearrangements of BCL1 and immunoglobulin heavy chain genes in the peripheral blood lymphocytes were detected at diagnosis, but not 1 or 4 years later. Further studies are required to confirm the role of low-dose CY therapy for patients with mantle cell leukemia and lymphoma. Am. J. Hematol. 63:35-37, 2000
  • Keywords
    thymoma , Goods syndrome , hypogammaglobulinemia , thrombocytosis , Pure red cell aplasia , macrocytic anemia
  • Journal title
    American Journal of Hematology
  • Serial Year
    2000
  • Journal title
    American Journal of Hematology
  • Record number

    25674