Title of article
Case Report: Osteomalacic Myopathy Associated with Coexisting Coeliac Disease and Primary Biliary Cirrhosis
Author/Authors
Demirag, Mehmet D. Gazi Üniversitesi - School of Medicine - Department of Internal Medicine, Section of Rheumatology, Turkey , Goker, Berna Gazi Üniversitesi - School of Medicine - Department of Internal Medicine, Section of Rheumatology, Turkey , Haznedaroglu, Seminur Gazi Üniversitesi - School of Medicine - Department of Internal Medicine, Section of Rheumatology, Turkey , Ozturk, Mehmet A. Gazi Üniversitesi - School of Medicine - Department of Internal Medicine, Section of Rheumatology, Turkey , Karakan, Tarkan Gazi Üniversitesi - School of Medicine - Department of Internal Medicine, Section of Gastroenterology, Turkey , Kuruoglu, Reha Gazi Üniversitesi - School of Medicine - Department of Neurology, Turkey
From page
425
To page
428
Abstract
Objective: To report a patient with coeliac disease (CD) associated with primary biliary cirrhosis (PBC) who presented with myopathy without classical symptoms of CD. Clinical Presentation and Intervention: A 42-year-old woman presented with inability to walk and marked loss of motor function. She had elevated liver enzymes with a cholestatic pattern. Antimitochondrial antibody M2 band, anti-endomysial antibody, antigliadin IgA and IgM were positive. Histopathologic findings of the liver revealed PBC and duodenal biopsy was consistent with CD. She was also found to have osteomalacia. She showed slow response to gluten-free diet, but accelerated full recovery with vitamin D replacement. Conclusion: In PBC patients with subclinical CD and myopathy, vitamin D status can provide a basis for treatment.
Keywords
Coeliac disease , Myopathy , Osteomalacia , Primary biliary cirrhosis , Vitamin D
Journal title
Medical Principles and Practice
Journal title
Medical Principles and Practice
Record number
2567906
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