Title of article
familial expression of spontaneous cervical artery dissections and ehlers-danlos syndrome hypermobile type
Author/Authors
hermanns-le, trinh unit of electron microscopy, department of dermatopathology, unilab lg, liege university hospital, liege, belgium - unit of electron microscopy, department of dermatopathology, unilab lg, liege university hospital, liege, belgium, Belgium , manicourt, daniel rheumatology department, saint-luc university hospital, brussels, belgium - rheumatology department, saint-luc university hospital, brussels, belgium, Belgium , e. pierard, gerald laboratory of skin bioengineering and imaging, department of clinical sciences, liege university, liege, belgium - laboratory of skin bioengineering and imaging, department of clinical sciences, liege university, liege, belgium, Belgium
From page
1
To page
3
Abstract
spontaneous cervical artery dissection (scad) and ehlers-danlos syndrome hypermobile type (edsh) represent two heritable clinical connective tissue disorders, which show some abnormal ultrastructural features in the dermis. genetic testing for most of those patients is not available at this time. we present a woman with scad and her five close relatives showing obvious or suggestive signs of edsh. in this family, the ultrastructural aspects of both diseases were closely related. alterations were present in both the aspect and spacing of collagen fibrils and in the shape of elastic fibers. the present familial combination of scad and edsh, with almost similar ultrastructural features suggests a possible connection between both conditions.
Keywords
skin , collagen , tissues , blood vessels , microscopy , electron ,
Journal title
Journal of Skin and Stem Cell
Journal title
Journal of Skin and Stem Cell
Record number
2579713
Link To Document