• Title of article

    Papillon-Lefèvre syndrome: A case report of two siblings and review of the literature

  • Author/Authors

    Sajad, Peerzada Government Medical College Srinagar (GMC) - Postgraduate Department of Dermatology, STD and Leprosy, India , Hassan, Iffat Government Medical College Srinagar (GMC) - Postgraduate Department of Dermatology, STD and Leprosy, India , Imtiyaz, Syed Government Medical College Srinagar (GMC) - Postgraduate department of Pathology, India

  • From page
    93
  • To page
    95
  • Abstract
    Papillon-Lefèvre syndrome is a rare autosomal recessive genodermatosis which is characterised by periodontitis, palmoplantar keratoderma and predisposition to pyogenic infections and occurs due to cathepsin C gene mutation (located on chromosome 11). The loss of primary teeth usually occurs by the age of 4 years and secondary teeth by second decade. The disorder is associated with significant cosmetic and functional disability.
  • Keywords
    Papillon , Lefèvre syndrome , periodontitis , palmoplantar keratoderma.
  • Journal title
    Journal of Pakistan Association of Dermatologists
  • Journal title
    Journal of Pakistan Association of Dermatologists
  • Record number

    2584310