Title of article
Screening of Terminalia bellirica Fruits Extracts for its Analgesic and Antipyretic Activities
Author/Authors
Sharma, Uma Shankar Sir Madanlal Group of Institutions - Department of Pharmacy, India , Sharma, Umesh Kumar Sir Madanlal Group of Institutions - Department of Pharmacy, India , Singh, Abhishek Sir Madanlal Group of Institutions - Department of Pharmacy, India , Sutar, Niranjan Sir Madanlal Group of Institutions - Department of Pharmacy, India , Singh, Puspak Jyoti Sir Madanlal Group of Institutions - Department of Pharmacy, India
From page
121
To page
124
Abstract
The study was designed to investigate the analgesic and antipyretic activities of ethanolic and aqueous extracts of Terminalia bellirica (family: Combrataceae) fruits (200 mg/kg, p.o.) in acetic acid-induced writhing, Eddy’s hot plate method and brewer s yeast-induced fever models in mice and rats. Both extracts showed a significant decrease in the number of the writhes in acetic acid-induced writhing and increase in paw licking time to heat stimuli in the hot plate method. Both extracts showed a significant inhibition of elevated body temperature when compared to corresponding control. The results suggested that the ethanolic and aqueous extracts possessed significant analgesic and antipyretic activities
Keywords
Terminalia bellirica , analgesic activity , acetic acid , induced writhing , hot plate method , antipyretic activity , brewer’s yeast , induced fever model
Journal title
Jordan Journal of Biological Sciences
Journal title
Jordan Journal of Biological Sciences
Record number
2584662
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