Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin‑induced renal toxicity in Wistar rats

Recently, we published an article in J Res Med Sci, entitled “Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin‑induced renal toxicity in Wistar rats.” In this article, it is concluded that metformin (MF) may prevent or ameliorate GM‑induced acute renal failure, and therefore, it might be beneficial in patients under treatment with this medicine. In this letter, we would like to point out a few points about the mentioned conclusion. In an agreement with our findings, Taheri et al. recently conducted a study on the effects of MF on renal function and structure after unilateral ischemia–reperfusion in rat.