Title of article
Synthesis, Characterization and Catalytic Behavior of some L-Hydroxyprolines Dimers for Asymmetric Aldol Reaction
Author/Authors
Al-Momani, Lo’ay A. Tafila Technical University - Department of Chemistry, Jordan
From page
289
To page
300
Abstract
Diesters derived from 4-L-hydroxyproline and malonic, succinic, glutaric or adipic acid are prepared and employed as enantioselective catalysts in the aldol reaction of pnitrobenzaldehyde with acetone. The catalytic properties are tested using different concentrations of the catalysts. A conversion of 50-100% and enantiomeric excess (ee) values of 74-84% are obtained with 20 % mol of the catalyst.
Keywords
Non , proteinogenic amino acid , organocatalysis , hydroxyproline , asymmetric aldol reaction
Journal title
Jordan Journal of Chemistry
Journal title
Jordan Journal of Chemistry
Record number
2585339
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