Biochemical Trails Associated with Different Doses of AlphaMonolaurin in Chicks

A study was conducted with one day old 40 broiler chicks (Ross308) to investigate body performance, biochemical parameters, lipid profiles, and cytokines changes associated with the different doses of alpha-monoglyceride (monolaurin) added to the diet of these chicks in a four week period. Three doses of monolaurin (C12,FRA)® were used; 2, 4, and 8 g/kg of diet. Results demonstrated that the recommended dose (4 g/kg of diet) significantly enhances body weight gain and food conversion ratio. Otherwise, two other doses have no significant effect on the considered parameters. The novel findings of this project were the improvement of pro-inflammatory cytokines (TNF-α and IL-12) and total antioxidant capacity (TAC) by monolaurin. Also, the recommended dose has hypolipidemic influence (except on triacylglycerol). It is concluded that chicken health is critically dependent on the gut condition, nutritional status, and immune defense. The recommended dose (4 g/kg) of monolaurin enhances chick performance and immunological and biochemical manifestations.