• Title of article

    Round Cell Vaginal Malignant Melanoma: A rare entity

  • Author/Authors

    Chauhan, Neena Himalayan Institute of Medical Sciences - Department of Pathology, India , Gaur, Dushyant S. Himalayan Institute of Medical Sciences - Department of Pathology, India , Pathak, Ved P. Himalayan Institute of Medical Sciences - Department of Pathology, India

  • From page
    508
  • To page
    511
  • Abstract
    Malignant melanoma is predominantly a skin disease but in rare instances it may occur at other sites. A vaginal melanoma is a rare clinical entity and the round cell type is an uncommon variant. Although the present case was clinically diagnosed as a urethral caruncle, on histopathological examination and immunostaining it was diagnosed as a round cell pigmented malignant melanoma. The patient refused radical surgery and was given a full course radiotherapy treatment but died a year later. Malignant vaginal melanoma carries a very poor prognosis even when lesion is localised at the time of presentation. The five-year survival rate ranges from 10–20% with the prognosis being influenced by tumour size. A tumour size ≥3cm has a poor prognosis. Age, mitotic count, stage, and location of the lesion do not influence survival rates
  • Keywords
    Melanoma , Vagina , Malignancy , Fontana , Masson stain , Immunohistochemical staining , Round cell tumors , Case report , India
  • Journal title
    Sultan Qaboos University Medical Journal (SQUMJ)
  • Journal title
    Sultan Qaboos University Medical Journal (SQUMJ)
  • Record number

    2592377