Pattern Electroretinographic Recordings in Eyes with Myopia

Purpose: Pattern electroretinography (PERG) is a specific test for the analysis of functionsof ganglion cells and macula. In this study, the authors investigated the PERG recordings inmyopia. Subjects and Methods: Four groups were formed according to the refraction of 160 eyesof 80 myopic and control subjects as follows: Group 1 (Controls): Between 0.00 and -0.75D; Group 2: -1.00 and -3.00 D; Group 3: -3.25 and -6.00 D; Group 4: -6.25 and 10.00 D. Amplitudes and latencies of P50 and N95 waves were recorded in all subjects. Results: P50 and N95 wave amplitudes were lower in high myopes (Groups 3 and 4) than low myopes (Groups 1 and 2; p 0.05). P50 and N95 wave latencies did not differ between the groups (p 0.05). Conclusion: Reduction in the amplitudes of P50 may be caused by macular dysfunction and reduction in the amplitudes of N95 may show the functional impairment of ganglion cells in high myopia.