Successful Treatment of Transient Central Diabetes Insipidus following Traumatic Brain Injury in a Dog

An 11-year-old female spayed Maltese presented comatose, half an hour afer vehicular trauma, and was treated for traumatic brain injury and pulmonary contusions. Te dog developed severe hypernatremia within six hours of presentation, which responded poorly to the administration of fve percent dextrose in water. As central diabetes insipidus was suspected, desmopressin was trialled and resolution of hypernatremia was achieved six days later. Transient trauma-induced central diabetes insipidus has been described previously in two dogs; in the frst, serum sodium concentrations were evaluated three days afer injury and the other developed hypernatremia seven days afer injury. To the authors’ knowledge, this is the frst report of rapid onset, transient, and traumainduced central diabetes insipidus in a dog that encompasses the complete clinical progression of the syndrome from shortly afer injury through to resolution.