Quetiapine-Induced Syndrome of Inappropriate Secretion ofAntidiuretic Hormone

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) can be induced by various conditions, includingmalignant neoplasms, infections, central nervous system disorders, and numerous drugs. We here report a case of a 65-year-oldfemale patient, treated with quetiapine for schizophrenia, who presented with generalized tonic-clonic seizures and was finallydiagnosed with quetiapine-induced SIADH. Quetiapine-associated hyponatremia is extremely uncommon and only a few, relevantreports can be found in the literature. This case underlines the fact that patients on antipsychotic medication and more specificallyon quetiapine should be closely monitored and routinely tested for electrolyte disorders.