Ambient Temperature Interferes with COVID‑19

Angiotensin‑converting enzyme 2 (ACE2) is a blood pressure regulating enzyme that attaches to the outer surface in cells of the lungs, arteries, kidney, heart, and intestines.[1] In addition to blood pressure regulating, ACE2 is involved in the pathophysiological processes by converting angiotensin isozymes during cell injury.[2] ACE2 converts angiotensin II to angiotensin‑(1‑7).[3] ACE2 also is a receptor for some coronaviruses including human coronavirus NL63 (HCoV‑NL63), severe acute respiratory syndrome‑associated coronavirus (SARS‑CoV), and SARS‑CoV‑2, the infectious agent of COVID‑19 (coronavirus Disease 2019) worldwide.[4] Many hypotheses have been made about COVID‑19. Underlying diseases such as hypertension, diabetes, and cancer, and environmental factors such as preventative methods and ambient temperature have been suggested to be involved into outbreak of COVID‑19. Because of the unclear treatment results and the panic following COVID‑19, some news about prevention and treatment strategies have been quickly spread among people through virtual networks.