• Title of article

    The Fractional Differential Model of HIV-1 Infection of CD4+ T-Cells with Description of the Effect of Antiviral Drug Treatment

  • Author/Authors

    Hasani Lichae, Bijan Department of Mathematics - Guilan Science and Research Branch - Islamic Azad University - Rasht, Iran , Biazar, Jafar Department of Applied Mathematics - Faculty of Mathematical Sciences - University of Guilan - Rasht - Guilan, Iran , Ayati, Zainab Department of Engineering Sciences - Faculty of Technology and Engineering East of Guilan - University of Guilan - Rudsar-Vajargah, Iran

  • Pages
    12
  • From page
    1
  • To page
    12
  • Abstract
    In this paper, the fractional-order differential model of HIV-1 infection of CD4+ T-cells with the effect of drug therapy has been introduced. There are three components: uninfected CD4+ T-cells, x, infected CD4+ T-cells, y, and density of virions in plasma, z. The aim is to gain numerical solution of this fractional-order HIV-1 model by Laplace Adomian decomposition method (LADM). The solution of the proposed model has been achieved in a series form. Moreover, to illustrate the ability and efficiency of the proposed approach, the solution will be compared with the solutions of some other numerical methods. The Caputo sense has been used for fractional derivatives.
  • Keywords
    CD4+ T-Cells , HIV-1 , Treatment , AIDS
  • Journal title
    Computational and Mathematical Methods in Medicine
  • Serial Year
    2019
  • Record number

    2612052