Title of article
Increased miR-188-3p in Ovarian Granulosa Cells of Patients with Polycystic Ovary Syndrome
Author/Authors
Dai, Beibei Department of Ultrasound - Obstetrics and Gynecology Hospital of Fudan University - Fangxie Road - Shanghai, China , Jiang, Jun School of Life Sciences - Fudan University - Shanghai, China
Pages
7
From page
1
To page
7
Abstract
MicroRNA-target networks are often dysregulated in diseases. Our purpose is to investigate this dysregulation of polycystic ovary
syndrome (PCOS). Through the bioinformatics reanalysis of the public RNAseq dataset, we found that miR-188-3p was the
miRNA with the highest induction rate, and indicated that miR-188-3p might have a rare function of upregulating its targeted
expression. This discovery will increase our understanding of the pathology of PCOS and provide new targets for treatment
strategies.
Keywords
miR-188-3p , Cell , Polycystic
Journal title
Computational and Mathematical Methods in Medicine
Serial Year
2021
Full Text URL
Record number
2615813
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