• Title of article

    Glanzmann’s Thrombastenia: The Role of Tranexamic Acid in Oral Surgery

  • Author/Authors

    Franco, Rocco Department of Biomedicine and Prevention - Section of Clinical Nutrition and Nutrigenomic - School of Applied Medical-Surgical Sciences - University of Rome Tor Vergata, Rome, Italy , Miranda, Michele Department of Systems Medicine - Medical School - University of Rome Tor Vergata, Rome, Italy , Di Renzo, Laura Department of Biomedicine and Prevention - Section of Clinical Nutrition and Nutrigenomic - School of Applied Medical-Surgical Sciences - University of Rome Tor Vergata, Rome, Italy , De Lorenzo, Antonino Department of Biomedicine and Prevention - Section of Clinical Nutrition and Nutrigenomic - School of Applied Medical-Surgical Sciences - University of Rome Tor Vergata, Rome, Italy , Barlattani, Alberta Department of Clinical Sciences and Translational Medicine -University of Rome Tor Vergata, Rome, Italy , Bollero, Patrizio Department of Systems Medicine - Medical School - University of Rome Tor Vergata, Rome, Italy

  • Pages
    5
  • From page
    1
  • To page
    5
  • Abstract
    Glanzmann’s thrombastenia (GT) is the most frequent inherited condition. GT is a genetic autosomal recessive disease caused by the alteration of the genes ITGA2B and ITGB3, located on the chromosome 17. The incidence of GT is calculated in 1 on 1000000. The patients, during their life, show episodes of mucocutaneous bleeding, epistaxis, and gingival bleeding. Some subjects required continuous bleeding transfusion. The aim of this case report is to demonstrate that oral assumption of tranexamic acid is a gold standard to prevent excessive bleeding. The patient GM of 36 years old with GT type 1 needs dental extractions of the teeth 4.7 and 4.8 at the “Tor Vergata” University Hospital in Rome. The specialist suggests that 3 days before surgery, the patient must take 6 vials every day of tranexamic acid that is used in obstetrics and gynecology. The teeth were extracted and applied suture. The patient is observed and is recommended mouth rinse with tranexamic acid. No bleeding complications were observed.
  • Keywords
    Glanzmann’s Thrombastenia , Tranexamic Acid , lanzmann’s Thrombastenia
  • Journal title
    Case Reports in Dentistry
  • Serial Year
    2018
  • Full Text URL
    downloads.hindawi.com/journals/crid/2018/9370212.pdf
  • Record number

    2616135

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2616135