• Title of article

    Adjunctive Hyperbaric Oxygen Therapy promotes successful healing in patients with refractory Crohn's disease

  • Author/Authors

    Feitosa, Marley Ribeiro Department of Surgery and Anatomy - Ribeirão Preto Medical School - University of São Paulo, Brazil , Féres, Omar Medical School of the Barão de Mauá University Center, Brazil , Tamaki, Camila Mussolin Hyperbaric Medicine Center, São Paulo, Brazil , Perazzoli, Camila Department of Surgery and Anatomy - Ribeirão Preto Medical School - University of São Paulo, Brazil , Bernardes, Mário Vinícius Angelete Alvarez Department of Surgery and Anatomy - Ribeirão Preto Medical School - University of São Paulo, Brazil , Parra, Rogério Serafim Department of Surgery and Anatomy - Ribeirão Preto Medical School - University of São Paulo, Brazil , Rocha, José Joaquim Ribeiro da Department of Surgery and Anatomy - Ribeirão Preto Medical School - University of São Paulo, Brazil , Féres, Omar Department of Surgery and Anatomy - Ribeirão Preto Medical School - University of São Paulo, Brazil

  • Pages
    5
  • From page
    19
  • To page
    23
  • Abstract
    PURPOSE: To investigate de adjunctive effect of Hyperbaric Oxygen Therapy in a group of patients with refractory Crohn's disease. METHODS: A total of 29 subjects with refractory Crohn's disease were submitted to daily sessions of Hyperbaric Oxygen Therapy, in a 2800 Sechrist Monoplace Hyperbaric Chamber (Sechrist, USA) pressurized to 2.4 ATA. Each session lasted 2 hours. The endpoint was closure of enterocutaneous fistulas and complete healing of Pyoderma Gangrenosum and perineal Crohn's disease. RESULTS: A total of 829 HBOT sessions were performed and no complications were noted. Overall success rate was 76% (22 cases). Pyoderma Gangrenosum and enterocutaneous fistulas had the highest successful healing rates (100% and 91%, respectively). Perineal Crohn's disease healing rate was 65%. CONCLUSION: Adjunctive Hyperbaric Oxygen Therapy promoted satisfactory healing in a group of patients with refractory Crohn's disease.
  • Keywords
    Hyperbaric Oxygenation , Crohn Disease , Cutaneous Fistula , Pyoderma Gangrenosum
  • Journal title
    Acta Cirurgica Brasileira
  • Serial Year
    2016
  • Full Text URL
    www.scielo.br/j/acb/a/bmmXMPVNLcxzs8KfNjWvbXS/?format=pdf&lang=en
  • Record number

    2616472

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2616472