Title of article
Oral Lichenoid Reaction: An Uncommon Side Effect of Rituximab
Author/Authors
Giudice, Amerigo Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Liborio, Francesco Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Averta, Fiorella Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Barone, Selene Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy , Fortunato, Leonzio Department of Health Sciences - School of Dentistry - Magna Graecia University of Catanzaro, Catanzaro, Italy
Pages
4
From page
1
To page
4
Abstract
Oral lichenoid reactions (OLR) can be caused by systemic drug exposure. To the best of our knowledge, this is the second report
describing a case of OLR induced by rituximab administration in a patient with a diagnosis of non-Hodgkin B-cell lymphoma.
After 5 doses of rituximab, a typical pattern of OLP was identified with bilateral and symmetrical lesions on the buccal mucosa
and on the right lingual margin. This temporal relationship suggested a probable association between oral lesions and drug
therapy. The clinical diagnosis of a rituximab-induced OLR was confirmed by an incisional biopsy reporting a histopathological
result of lichenoid mucositis consistent with oral lichen planus. Because of the increasing use of rituximab, it is necessary to
know and recognize this uncommon side effect.
Keywords
Oral Lichenoid Reaction , Uncommon Side Effect , Rituximab
Journal title
Case Reports in Dentistry
Serial Year
2019
Full Text URL
Record number
2618531
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