Title of article
Chlorpyrifos chronic toxicity in broilers and effect of vitamin C
Author/Authors
Kammon, A.M. Al-Fateh University - Faculty of Veterinary Medicine - Department of Poultry and Fish Diseases, Libya , Brar, R.S. Guru Angad Dev Veterinary Animal Sciences University (GADVASU) - College of Veterinary Science - Department of Veterinary Pathology, India , Sodhi, S. Guru Angad Dev Veterinary Animal Sciences University (GADVASU) - College of Veterinary Science - Department of Veterinary Pathology, India , Banga, H.S. Guru Angad Dev Veterinary Animal Sciences University (GADVASU) - College of Veterinary Science - Department of Veterinary Pathology, India , Singh, J. University of Saskatchewan - Western College of Veterinary Medicine - Department of Biomedical Sciences, Canada , Nagra, N.S. Guru Angad Dev Veterinary Animal Sciences University (GADVASU) - College of Veterinary Science - Department of Livestock Production and Management, India
From page
21
To page
27
Abstract
An experiment was conducted to study chlorpyrifos chronic toxicity in broilers and the protective effect of vitamin C. Oral administration of 0.8 mg/kg body weight (bw) (1/50 LD50) chlorpyrifos (Radar®), produced mild diarrhea and gross lesions comprised of paleness, flaccid consistency and slightly enlargement of liver. Histopathologically, chlorpyrifos produced degenerative changes in various organs. Oral administration of 100 mg/kg bw vitamin C partially ameliorated the degenerative changes in kidney and heart. There was insignificant alteration in biochemical and haematological profiles. It is concluded that supplementation of vitamin C reduced the severity of lesions induced by chronic chlorpyrifos toxicity in broilers.
Keywords
chlorpyrifos , chronic toxicity , clinicopathology , vitamin C , broilers.
Journal title
Open Veterinary Journal
Journal title
Open Veterinary Journal
Record number
2619413
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