• Title of article

    Structural investigation of methyl 3-(4-fluoro­benzo­yl)-7-methyl-2-phenyl­indolizine-1-carboxyl­ate, an inhibitory drug towards Mycobacterium tuberculosis

  • Author/Authors

    Hasija, Avantika Department of Chemistry - Indian Institute of Science Education and Research Bhopal, India , Bhandary, Subhrajyoti Department of Chemistry - Indian Institute of Science Education and Research Bhopal, India , Venugopala, Katharigatta N. Department of Pharmaceutical Sciences - College of Clinical Pharmacy - King Faisal University, Kingdom of Saudi Arabia , Chandrashekharappa, Sandeep Institute for Stem Cell Biology and Regenerative Medicine, India , Chopra, Deepak Department of Chemistry - Indian Institute of Science Education and Research Bhopal, India

  • Pages
    11
  • From page
    1
  • To page
    11
  • Abstract
    The title compound, C24H18FNO3, crystallizes in the monoclinic centrosymmetric space group P21/n and its mol­ecular conformation is stabilized via C—H⋯O intra­molecular inter­actions. The supra­molecular network mainly comprises C—H⋯O, C—H⋯F and C—H⋯π inter­actions, which contribute towards the formation of the crystal structure. The different inter­molecular inter­actions have been further analysed via Hirshfeld surface analysis and fingerprint plots.
  • Keywords
    fingerprint plot , crystal structure , anti-TB activity drug , nter­molecular inter­actions , Hirshfeld surface analysis
  • Journal title
    Acta Crystallographica Section E: Crystallographic Communications
  • Serial Year
    2020
  • Full Text URL
    journals.iucr.org/e/issues/2020/04/00/xi2021/xi2021.pdf
  • Record number

    2624331

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2624331