Cutaneous graft-versus-host disease on 7th day of blood transfusion in an adult male

Graft-versus-host disease (GVHD) occurs when immunologically competent cells are introduced into an immunoincompetent host. The leading cause of GVHD is hematopoietic cell transplantation (HCT). Solid organ transplants, blood transfusions, and maternal-fetal transfusions also reportedly cause GVHD. We report a case of a 58-year-old male who presented with large erythematous to violaceous papules and plaques scattered on trunk and limbs, on the 7th day of whole blood transfusion. There was no evidence of systemic involvement. Diagnosis was confirmed on histopathological findings of skin lesion. Patient was treated with local steroids with resolution of lesions