Title of article
Clinical pathologies of breast cancer in the elderly and youths and their prognosis
Author/Authors
Ji, Hong Second Hospital of Hebei Medical University - Department of General Surgery, China , Ai, Ning Fourth Hospital of Hebei Medical University - Department of Radiology, China , Li, Qinghuai Second Hospital of Hebei Medical University - Department of General Surgery, China , Zhang, Kaili Second Hospital of Hebei Medical University - Department of General Surgery, China , Di, Wang Second Hospital of Hebei Medical University - Department of General Surgery, China
From page
535
To page
538
Abstract
Objective: To explore the correlation between the clinical pathologies of breast cancer in the elderly and youths as well as their prognosis. Methods: Two hundred and eighty breast cancer patients were divided into a youth group ( 60, n=120) and an elderly group (≥ 60, n=160) according to the age. Their routine clinical pathological indices and immune indices were observed and determined, and the prognosis was observed after effective treatment. Results: The positive expression rates of p63, CK5/6, CK14 and CK17 in the elderly group were significantly higher than those of the youth group (P 0.05). The tumor-free survival rate of the youth group (95.8%) was significantly higher than that of the elderly group (84.4%) (P 0.05). Multivariate Logistic regression analysis showed that the positive expressions of p63 and estrogen receptor, age, and postoperative chemotherapy were the independent risk factors of tumor-free survival rate (P 0.05). Conclusion: The immunohistochemical typing characteristics of the elderly and youths were different, and the prognosis of young patients was better, being correlated with the typing.
Keywords
Age , Breast cancer , Immunohistochemistry , Pathological characteristics , Prognosis
Journal title
Pakistan Journal of Medical Sciences
Journal title
Pakistan Journal of Medical Sciences
Record number
2643374
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