Title of article
ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIVITIES OF ETHANOLIC ROOT EXTRACT OF CROTON ZAMBESICUS
Author/Authors
OKOKON, JUDE E University of Uyo - Department of Pharmacology and Toxicology, Nigeria , NWAFOR, PAUL A University of Uyo - Department of Pharmacology and Toxicology, Nigeria
From page
385
To page
392
Abstract
The ethanolic root extract of C. zambesicus (27-81mg/kg) was evaluated for antiiflammatory, analgesic and antipyretic properties in mice. The extract (27-81mg/kg) demonstrated a weak antiinflammatory activity. However, a significant (P 0.01-0.001) analgesic and antipyretic activities were observed in all the experimental models tested. The extract may be exerting its effects through central mechanisms. These findings confirms its ethnomedical use in the treatment of malarial-associated symptoms.
Keywords
Antiinflammatory , analgesic , antipyretic , Croton zambesicus
Journal title
Pakistan Journal Of Pharmaceutical Sciences
Journal title
Pakistan Journal Of Pharmaceutical Sciences
Record number
2647374
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