Title of article
Evaluation of anti-inflammatory activity of selected legumes from Pakistan: In vitro inhibition of Cyclooxygenase-2
Author/Authors
Zia-Ul-Haq, Muhammad University of Karachi - Department of Pharmacognosy, Pakistan , Landa, Premysl Institute of Experimental Botany AS CR - Laboratory of Plant Biotechnologies, Czech Republic , Kutil, Zsófia Institute of Experimental Botany AS CR - Laboratory of Plant Biotechnologies, Czech Republic , Kutil, Zsófia Czech University of Life Sciences Prague - Institute of Tropics and Subtropics - Department of Crop Sciences and Agroforestry, Czech Republic , Qayum, Mughal Abdul Wali Khan University Mardan - Department of Pharmacy, Pakistan , Ahmad, Shakeel Bahauddine Zakariya University - Department of Agronomy, Pakistan
From page
185
To page
187
Abstract
Crude methanolic extracts of selected legumes namely, black gram (Vigna mungo L.), green gram (Vigna radiata (L.) R. Wilczek ), soybean (Glycine max (L.) Merr.) and lentil (Lens culinaris Medik.) were investigated for antiinflammatory effects, using COX-2 producing PGE2 inhibitory assay. Percentage inhibition observed was 73.93, 79.84, 92.17 and 74.47 for black gram, green gram, soybean and lentil respectively at 20μg/ml extract concentration. The 100μg/ml concentration showed increase in the percent inhibition except for soybean. This is the first report on COX-2 inhibitory potential of food legumes.
Keywords
Anti , inflammatory , legumes , COX , 2 , lentil , soybean , black gram , green gram
Journal title
Pakistan Journal Of Pharmaceutical Sciences
Journal title
Pakistan Journal Of Pharmaceutical Sciences
Record number
2647665
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