Causative Organisms of Urinary Tract Infection and their Sensitivity Pattern in Children

Objective: To determine the pattern of different causative organisms in urinary tract infection and their antibiotic sensitivity pattern among children. Study duration and setting: Study was completed in Six months i.e. from June to December 2015 in department of Pediatrics, Shaikh Khalifa Bin Zayed Al-Nahyan Hospital, Muzaffarabad. Methodology: A total of 370 children with suspicion of urinary tract infection were included. Mid-stream, clean catch specimens were collected in a sterilized container. Urine sample was delivered to laboratory immediately for detection of causative organism. Susceptibility testing was carried out to routinely used antibiotics. Data was entered and analyzed on SPSS 20. Results: The mean age was 5.42 ± 2.043 years ranged from 2 to 9 years. There were 200 (54.1%) female patients. The causative organisms responsible for urinary tract infection were E Coli (47.6%) followed by Klebsiella (23.2%) and Proteus (10%), Staphylococcus was found in (7.3%) and Enterobacter in (7.3%) children, and rest (4.6%) were effected with other organisms. Meropenum 286 (77.3%) and Ceftazidine286 (77.3%) showed highest sensitivity and lowest resistance pattern followed by Levofloxacin 285 (77.0%), Imipenem 284 (76.8%) and Amikacin 279 (75.4%) respectively. There was no statistically significant (p-value 0.05) association of age and gender with organism responsible for UTI. Conclusion: E Coli is more common causative organism for urinary tract infection followed by Klebsiellaand Staphylococcus. Highest sensitivity pattern was found with Meropenem, Ceftazidine, Levofloxacin, Imipenem and Amikacin.