Title of article
Synthesis and study of biological activity of some new Imidazole derivatives
Author/Authors
atia, abdul jabar kh. al- mustansiriya university - college of science - department of chemistry, iraq , al-marjani, mohammed fraj al- mustansiriya university - college of science - department of biology, iraq , qaban, muayad abbood al- mustansiriya university - college of science - department of chemistry, iraq
From page
547
To page
555
Abstract
In this work ester derivatives were synthesized by the reaction of imidazole derivatives (C1) with ethylchloroacetate in ethanol and NaOH to give the corresponding (C2) .While compound (C3) acetohydrazide was synthesized by the reaction of ester derivatives (C2) with hydrazine hydrat in ethanol. Compound (C3) from the reaction with different aromatic aldehydes in absolute ethanol gave the Schiff′s bases (C4,C5). The product compounds were characterized by FT-IR, U.V and 1HNMR spectra and the biological activities were studied as antibacterial.
Keywords
acetohydrazide , Schiff′s bases , Imidazole.
Journal title
Baghdad Science Journal
Journal title
Baghdad Science Journal
Record number
2691823
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