Author`s Reply:Unusual evolution of bulb-shaped echoluscent-structured nonobstructive prosthetic valve thrombosis under thrombolytic therapy

As we indicated in our article, there is no consensus about the treatment of patients with PVT in the guidelines. Guidelines recommend that taken into consideration of thrombus size, location and the patient s clinical status before receiving medical or surgical treatment decision (1). But there is no recommendation about the age of thrombus. In addition, there are no clear recommendations about dose and duration of treatment for patients who undergoing thrombolytic therapy. TROIA study made by Özkan et al.