Title of article
Epidermodysplasia verruciformis: a rare disease
Author/Authors
Jowkar, Farideh Department of Dermatology - Shiraz University of Medical Sciences - Shiraz, Iran , Ahmadi Mahmoodabadi, Razieh Department of Dermatology - Shiraz University of Medical Sciences - Shiraz, Iran , Fazelzadeh Haghighi, Negin Department of Dermatology - Shiraz University of Medical Sciences - Shiraz, Iran
Pages
2
From page
252
To page
253
Abstract
Epidermodysplasia verruciformis (EV), also
known as tree man syndrome, is a very rare
autosomal recessive disease characterized by
increased susceptibility to certain types of the
human papillomavirus (HPV) 1,2. Many different
types of HPV have been shown to be responsible
for cutaneous lesions of EV including types 3,
5, 8, 10, 9, 12, 14, 15, 17, 19-25, 28, 29, 36, 38, 46,
47, 49, and 50 3. In EV, there are mutations in the
EVER1/TMC6 and EVER2/TMC8 genes located
on chromosome 17q25 that lead to cell-mediated
immunity defects and an unusual susceptibility
to certain types of HPV 2-4.
Keywords
Epidermodysplasia , EVER1/TMC6 , HPV
Journal title
Iranian Journal of Dermatology
Serial Year
2021
Record number
2700369
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