Oral Bacteria and Colorectal Pathology

The oral cavity and colon are distantly located anatomically and are hence colonized by entirely divergent microbes. The mouth is affected by several pathologies, and so is the colon. Therefore, it is quite natural to investigate the potential connection between poor oral health and colorectal pathologies. Evidence Acquisition: This article is a small attempt to identify the oral microbiota, how they translocate to the colorectal area, and how they give rise to pathology. PubMed indexed journals relating to this topic were screened and shortlisted to construct this article. Results: The organisms generally responsible for oral diseases, particularly Fusobacterium nucleatum and Porphyromonas gingivalis, have been found in colon disorders resulting in intestinal dysbiosis and ultimately leading to colorectal cancer. Conclusion: If the disease pathogenesis is well understood, it will open new ways to prevent or treat colorectal pathologies. However, further studies are needed in this arena