Title of article
chronic myeloid leukemia in a young man with unusual presentation of weight loss with bone and abdominal pain
Author/Authors
mohamadian, niloufar islamic azad university, kermanshah branch - young researchers and elite club, kermanshah, iran , seyedmoradi, mehdi islamic azad university, kermanshah branch - young researchers and elite club, kermanshah, iran , izadi, babak kermanshah university of medical sciences - molecular pathology research center, imam reza hospital, kermanshah, iran , amirian, farhad kermanshah university of medical sciences - molecular pathology research center, imam reza hospital, kermanshah, iran , ramezani, mazaher kermanshah university of medical sciences - molecular pathology research center, imam reza hospital, clinical research development center - department of molecular pathology, kermanshah, iran
From page
51
To page
54
Abstract
chronic myeloid leukemia (cml) is a clonal myeloproliferative neoplasm and one of the main subtypes of leukemia that mainly affects adults. the incidence of cml increases slowly with age until the middle of the fourth decade, and then it rises rapidly. anemia, splenomegaly, and constitutional symptoms are the most common signs and symptoms at presentation. here we report a 27-year-old man with bone pain and generalized abdominal pain. he also had weight loss because of anorexia and easy satiety. the qualitative probe-based real-time pcr (qrt-pcr) result was positive for bcr-abl1 (t9:22) p210 mutation. the patient was treated with imatinib, the standard first-line treatment for cml, and showed clinical improvement. his pain also decreased, and he was discharged in good condition.
Keywords
bone pain , chronic myeloid leukemia , cml , weight loss
Journal title
Basic and Clinical Cancer Research
Journal title
Basic and Clinical Cancer Research
Record number
2704630
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