Title of article
In vivo lung injury caused by Pseudomonas aeruginosa DNA
Author/Authors
Al-Mathkhury, Harith Jabbar Fahad University of Baghdad - College of Science - Department of Biology, Iraq
Pages
5
From page
794
To page
798
Abstract
Noticeable inflammatory reactions in rats lungs were caused by DNA isolated from Pseudomonas aeruginosa include infiltration of macrophages, neutrophiles and lymphocytes. Additionally, fibromuscular hypertrophy of smooth muscles in respiratory bronchiols was seen as well. Since lung homogenate shows no bacterial growth in all samples. Consequently, these inflammatory signs were attributed to DNA effect rather than any other cause. In conclusion, apart from live bacteria, P. aeruginosa DNA has the ability to cause inflammatory response in rat model airways.
Keywords
lung , Pseudomonas aeruginosa , DNA
Journal title
Iraqi Journal Of Science
Serial Year
2012
Journal title
Iraqi Journal Of Science
Record number
2711212
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