Prevalence of Helicobacter Pylori Gastritis at the North of Jordan

Helicobacter pylori was isolated from different gastric patients at the north of Jordan. Cultural and histological studies revealed a positive H. pylori infection in 78% of the collected samples. Clinical diagnosis showed that 21.6% of H. pylori patients were suffering from gastroduodenitis. Histological examination of collected mucosa showed that 67% of H. pylori positive patients were having acute and chronic gastritis, whereas 18.3% and 15% of them were suffering from intestinal metaplasia and atrophy, respectively. So, the highest specificity was 84% which was seen in histology results compared to microscopy. However, 58% of infected persons were males and the highest incidence of infection was found in the age 25- 35 years old. Isolated H. pylori cells were found sensitive to tetracycline, amoxicillin and clarithromycin with an MIC of 0.15, 0.12 and 0.015 μg/ml, respectively.