Title of article
Sulphamic Acid (H2NSO3H) Catalysed One Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and Their Thione Analogues
Author/Authors
Kotharkar, Sandeep A. Dr. Babasaheb Ambedkar Marathwada University - Department of Chemical Technology, India , Jadhav, Mohan. R. Dr. Babasaheb Ambedkar Marathwada University - Department of Chemical Technology, India , Nagawade, Rahul R. Wockhardt Research Centre, India , Bahekar, Sushilkumar S. National Chung Cheng University, - Department of Chemistry and Biochemistry, Taiwan , Shinde, Devanand B. Dr. Babasaheb Ambedkar Marathwada University - Department of Chemical Technology, India
From page
662
To page
664
Abstract
The substituted 3,4-dihydropyrimidin-2(1H)-ones and their thione analogues have been prepared Via Biginelli condensation using aldehyde, 1,3-dicarbonyl compound and urea or thiourea under the catalystof sulphamic acid (H2NSO3H). The method is simple, cost-effective, and gives good yields in a shorter reactiontime.
Keywords
Sulphamic acid , catalyst , Biginelli reaction
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2717923
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