Title of article
A Concise Total Synthesis of 7-Substituted Eudistomin Analogs
Author/Authors
Peng, Zuozhong Wu Xi Pharma Tech Co., Ltd., China , Song, Ji 1WuXi Pharma Tech Co., Ltd., China , Liao, Wensheng Wu Xi PharmaTech Co., Ltd., China , Ma, Rujian Wu Xi PharmaTech Co., Ltd., No., China , Chen, Shu-Hui Wu Xi PharmaTech Co., Ltd., China , Li, Ge Wu Xi PharmaTech Co., Ltd., China , Ando, Ryoichi Mitsubishi Pharma Corporation, Japan
From page
455
To page
458
Abstract
We report herein an optimized practical synthesis of three novel 7-substituted eudistomin analogs(1-3). The total syntheses of these complex tetracyclic molecules were completed in 22 steps from the requisite7-substituted indoles.
Keywords
Eudistomin analogs , total Synthesis , Pictet , Spengler cyclization , diasteroselectivity , demethylation
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2718025
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