Title of article
Facile Synthesis of C3-Symmetric Tripodal β-Hydroxy Amide Ligands and Their Ti (IV) Complex-Catalyzed Asymmetric Addition of Diethylzinc to Aldehydes
Author/Authors
Fang, Tao Peking University - College of Chemistry and Molecular Engineering - Key Laboratory of Bioorganic Chemistry andMolecular Engineering, Beijing National Laboratory for Molecular Sciences (BNLMS), China , Xu, Jiaxi Peking University - College of Chemistry and Molecular Engineering - Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering, China , Du, Da-Ming Peking University - College of Chemistry and Molecular Engineering - Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering, China
From page
780
To page
786
Abstract
Chiral C3-symmetric tripodal tris(b-hydroxy amide) ligands have been conveniently synthesized viathe reaction of 1,3,5-benzenetricarboxylic chloride and chiral amino alcohols, and the corresponding tris(amino alcohol) ligands were obtained via the borane reduction of amides. The asymmetric diethylzinc addition to various aldehydes catalyzed by these chiral ligand-Ti (IV) complexes gave modestenantioselectivities.
Keywords
C3 , symmetry , b , hydroxy amide , amino alcohol , asymmetric synthesis , diethylzinc
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2718077
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